Rune

Runes are demonic sigils in Doom (2016) which upgrade the Doom marine's intrinsic abilities. There are twelve distinct runes, each of which must be earned by finding its rune stone, a green glowing monolith bearing the runic mark, and defeating the ensuing rune trial, typically a battle which occurs in a small enclosed space disconnected from other game play areas. The runes are passive permanent upgrades, but only a certain number can be equipped at a given time, based on the Praetor suit's current capabilities. A maximum of three runes can be equipped when the protagonist is at full power.

Multiplayer
Runes are introduced in Update 6.66, replacing hack modules. Runes now last throughout the user's life instead of single-use and they are unlocked with player's progression. Their effects are greatly simplified as well, as they are no longer ranked by tiers and some effects from hack modules are combined together. Up to three slots are provided to the player once unlocked.

Runes are not available in Clan Arena and Infernal Run.

Trivia
The runes are loosely based on s and diabolical seals used in, as derived from various medieval s and the well-known 17th century occult book, the . None of the runes exactly match actual known sigils, however.