→List of Champions and abilities
* '''Major''' (Heavy) -- Air Strike, Wall Climb, Tall Lean & Mean
* '''Serious Sam''' (Heavy) -- Complementary Ammo, Seriously Loaded, Serious Minigun
Active abilities are:
* '''Air Strike''': Major can summon bombs that fall on locations she marks by using the "fire" key.
* '''Serious Minigun''': Serious Sam brings out his trademark minigun to fill enemies with lead. Hourglasses don't reduce its cooldown, but grants ammo for the minigun instead.
Passive abilities are:
* '''Complementary Ammo''': Medium and large armor pickups refill ammo for Serious Sam's currently equipped weapon.
* '''Seriously Loaded''': Serious Sam starts with all three starting weapons.
== Monster replacement ==