Mancubuses are real powerhouses, with extremely high health and a powerful ranged attack with a reasonably high rate of fire. Players are fully justified in using their most high-powered weaponry to bring one down. The weapons that are effective against the Mancubus are the [[Chaingun (Doom 3)|Chaingun]], the [[Rocket launcher (Doom 3)|Rocket launcher]], [[Plasma Gun]], and the [[BFG 9000 (Doom 3)|BFG]]. Headshots are effective and quite easy to score on a Mancubus, since they are a slow moving and very large target. A Mancubus can be killed with about 4 rocket launcher headshots. If the [[Soul Cube]] or [[Artifact]] is available, by all means use it.